does hrt cause hair loss
By Tamim Hamid Last Updated on 11/06/2024

Does HRT Cause Hair Loss? Effects of Hormone Replacement Therapy

Hormone Replacement Therapy (HRT): a miracle for menopause symptoms or a potential trigger for hair loss?

HRT is a treatment commonly recommended for women of a certain age, particularly those going through menopause. Designed to alleviate symptoms like hot flashes, mood swings, and bone loss that arise from declining estrogen and progesterone levels, HRT aims to restore hormonal balance during this life phase.

For many women, it’s a pathway to improved comfort and quality of life.
But here’s the twist: the debate around HRT and hair loss is one that has left many scratching their heads – both figuratively and literally. You sign up for relief from hot flashes and mood swings, but then you catch sight of extra hair strands clogging your shower drain, and suddenly you're wondering if HRT is doing more harm than good.

While HRT works wonders for balancing hormones like estrogen and progesterone, the body’s response is anything but one-size-fits-all. For some, the treatment can lead to improved hair growth, restoring fullness. But for others, it’s like that one unexpected side effect on the medication bottle: thinning hair. And no, it’s not all in your head – certain types of HRT, especially those containing synthetic progestogens with androgenic effects, have been known to contribute to hair thinning, particularly for those predisposed to androgen sensitivity.

So, what's the real deal? How does HRT impact your hair health, and more importantly, what can you do to regain control if your treatment seems to be sabotaging your scalp?

How Does HRT Work?

Hormone Replacement Therapy (HRT) is like hitting the "reset" button for your body’s hormones during menopause. When estrogen and progesterone levels start to decline, it can trigger everything from night sweats and mood swings to bone loss. HRT steps in to top off those hormonal tanks, stabilizing levels and offering much-needed relief from menopausal symptoms.

Estrogen plays a key role not just in managing mood or regulating menstrual cycles but also in hair health. It prolongs the anagen phase, the active growth period of hair, promoting fuller, thicker strands. But when menopause causes estrogen to dip, you may start noticing more hair in your brush than on your head. And that’s where HRT aims to help: by restoring estrogen levels, it can improve hair growth and density.

But there's a catch. The balance of hormones is a delicate one. If the wrong type or dosage of HRT is used, it can lead to HRT and thinning hair, especially if the therapy includes synthetic progestogens with androgenic properties that may increase levels of DHT – a hormone infamous for shrinking hair follicles.

Can HRT Cause Hair Loss?

Yes, HRT can cause hair loss – but let’s not throw the baby out with the bathwater just yet.

The effect of HRT on your hair is highly individualized, and several factors come into play, including your hormone balance, genetics, and the type of HRT you're on. The key lies in the relationship between hormone imbalance and hair loss.

You see, hormones are the conductors of your body’s orchestra. When they’re in tune, everything works harmoniously. But during menopause, estrogen and progesterone levels drop, and that’s when things can get out of whack – not only causing menopausal hair loss but also potentially affecting how you respond to HRT.

Interestingly, certain HRT formulations, particularly those with synthetic progestogens (synthetic progesterone-like hormones) that have androgenic effects, can contribute to hair thinning in some individuals. Androgens, like testosterone, can be converted into DHT (dihydrotestosterone) – a hormone that’s notorious for shrinking hair follicles and speeding up hair shedding. If you’re genetically sensitive to androgens, you might notice hair loss when taking these types of HRT​.

But let’s not jump to conclusions. Not all HRT leads to hair loss. In fact, many women find that HRT actually improves their hair by restoring their hormone levels to a more balanced state. For those experiencing menopausal hair loss, the introduction of estrogen-based HRT can extend the anagen phase (the active growth phase of hair) and reduce hair thinning​.

How Does Hormone Therapy Cause Hair Loss?

While HRT can work wonders for menopausal symptoms, it can also have some unexpected effects on your hair. Hormones can be, let’s say, a little temperamental. And when you’re taking HRT, your hair follicles might feel the brunt of it. Here’s a breakdown of how hormone therapy can stir up hair loss:

1. Hormonal Imbalance

Balancing hormones is like walking a tightrope – a little shift either way, and you’re thrown off balance. When HRT changes your body’s levels of estrogen and progesterone, hair growth cycles can be disrupted. Estrogen typically prolongs the growth (anagen) phase of hair, and when it’s off-kilter, hair can enter the shedding phase prematurely​.

So, if those hormones aren’t at their happy levels, expect a little chaos on your scalp.

2. Androgenic Effects

Some forms of HRT include synthetic hormones that have androgenic effects – meaning they can act like androgens (male hormones). These synthetic progestogens can increase levels of DHT, the notorious hormone responsible for shrinking hair follicles and, yes, causing hair thinning. This is particularly true for those using testosterone HRT as part of their therapy. Higher DHT means follicles are less able to produce healthy, thick hair strands

3. Individual Sensitivity

Everyone’s got their kryptonite. For some, it's peanut butter; for others, it’s HRT. Individuals vary greatly in their sensitivity to hormones, and some may be more prone to hair loss when faced with androgenic hormones. So, while one person might sail through HRT with hair intact, another could find themselves dealing with unwanted thinning due to heightened androgen sensitivity. It's about how your hair follicles respond to those hormonal shifts.

4. Telogen Effluvium

And then there's telogen effluvium, a condition where hair follicles are pushed into the resting and shedding phase too quickly. This is often triggered by sudden changes in hormone levels – say, when starting or altering HRT. The result is hair shedding that feels a bit like someone flipped a switch, leading to diffuse thinning. The good news is that telogen effluvium is usually temporary, but it’s enough to make you rethink your current hair care routine.

How to Treat HRT-Related Hair Loss

First things first: don’t let a few extra hairs on your pillow send you into panic mode. If HRT is causing hair thinning, there are practical ways to slow or reverse the process.

Let’s get into the details of addressing HRT-related hair loss with some scientifically-backed solutions.

1. Adjust Hormone Therapy

HRT isn’t a one-size-fits-all. If you’re dealing with thinning hair, consult your healthcare provider about the type and dosage of hormones you're taking. Sometimes, a simple tweak to the therapy can balance your estrogen, progesterone, and androgen levels, reducing the chances of hair shedding caused by DHT – that pesky hormone associated with DHT and female hair loss.

2. Topical Treatments

One of the most effective treatments to help regrow hair is the use of topical treatments like minoxidil (you may know it as Rogaine™). It’s proven to stimulate hair follicles and promote regrowth by prolonging the anagen phase (growth phase) of your hair cycle.

Your doctor can guide you on the right formulation and application routine for the best results.

3. Scalp Care

Healthy hair starts with a healthy scalp. Regular scalp care can make a huge difference in hair health – so think gentle shampoos, minimal chemical styling, and regular scalp massages to increase blood circulation. Massaging the scalp with natural oils like jojoba or castor oil can encourage blood flow and improve follicle health, a practical step in reversing menopausal hair loss.

4. Laser Phototherapy

Also known as Low-Level Laser Therapy (LLLT), laser phototherapy is a scientifically proven treatment that can stimulate hair follicles, encourage growth, and improve overall scalp health.

While at-home laser combs and helmets are available, professional treatments often yield more noticeable results. LLLT has been shown to be effective in extending the growth phase and reducing hair loss related to hormonal imbalances.

5. Nutritional Support

What you eat plays a major role in how your hair behaves. Nutrient deficiencies, especially in biotin, iron, zinc, omega-3 fatty acids, and vitamins A, C, and D, can contribute to hair thinning and loss. A balanced diet with plenty of whole foods, leafy greens, nuts, and lean proteins is vital for keeping your hair strong and healthy. Supplements can help fill in any gaps in your diet, but it’s always best to consult with a healthcare provider before adding any new supplement to your regimen.

Conclusion

While HRT and hair loss can go hand in hand for some, it’s not the case for everyone. Your hair’s response to HRT will depend on a variety of factors – from your genetic predisposition to the type of therapy you’re on. If HRT seems to be affecting your hair health, consult your doctor about adjusting your treatment. And remember, a balanced diet, scalp care, and additional treatments can support your hair through the hormonal ups and downs.

Tamim Hamid

Tamim Hamid

Inventor and CEO of Theradome

Sayyid Tamim Hamid, Ph.D, is the inventor of the world’s first FDA-cleared, wearable phototherapy device to prevent hair loss and thicken and regrow hair. Tamim, a former biomedical engineer at NASA and the inventor of Theradome, brings with him more than 38 years of expertise in product development, laser technology, and biomedical science. Tamim used his laser knowledge, fine-tuned at NASA, and combined it with his driving passion for helping others pursue a lifelong mission in hair loss and restoration. He is now one of the world’s leading experts.